Detalhe da pesquisa
1.
Cryo-EM Structure of the Human Cannabinoid Receptor CB2-Gi Signaling Complex.
Cell
; 180(4): 645-654.e13, 2020 02 20.
Artigo
Inglês
| MEDLINE | ID: mdl-32004460
2.
Structure of nucleosome-bound DNA methyltransferases DNMT3A and DNMT3B.
Nature
; 586(7827): 151-155, 2020 10.
Artigo
Inglês
| MEDLINE | ID: mdl-32968275
3.
DNA strand asymmetry generated by CpG hemimethylation has opposing effects on CTCF binding.
Nucleic Acids Res
; 51(12): 5997-6005, 2023 07 07.
Artigo
Inglês
| MEDLINE | ID: mdl-37094063
4.
Crystal structure of the Frizzled 4 receptor in a ligand-free state.
Nature
; 560(7720): 666-670, 2018 08.
Artigo
Inglês
| MEDLINE | ID: mdl-30135577
5.
Dimerization of the transmembrane domain of amyloid precursor protein is determined by residues around the γ-secretase cleavage sites.
J Biol Chem
; 292(38): 15826-15837, 2017 09 22.
Artigo
Inglês
| MEDLINE | ID: mdl-28790170
6.
Defining the minimum substrate and charge recognition model of gamma-secretase.
Acta Pharmacol Sin
; 38(10): 1412-1424, 2017 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-28414207
7.
Amyloid beta: structure, biology and structure-based therapeutic development.
Acta Pharmacol Sin
; 38(9): 1205-1235, 2017 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-28713158
8.
Structure of an AMPK complex in an inactive, ATP-bound state.
Science
; 373(6553): 413-419, 2021 07 23.
Artigo
Inglês
| MEDLINE | ID: mdl-34437114
9.
Structure of formylpeptide receptor 2-Gi complex reveals insights into ligand recognition and signaling.
Nat Commun
; 11(1): 885, 2020 02 14.
Artigo
Inglês
| MEDLINE | ID: mdl-32060286
10.
Bioluminescence Resonance Energy Transfer (BRET) Assay for Determination of Molecular Interactions in Living Cells.
Bio Protoc
; 7(22)2017 Nov 20.
Artigo
Inglês
| MEDLINE | ID: mdl-29423426
11.
γ-Secretase Epsilon-cleavage Assay.
Bio Protoc
; 7(22)2017 Nov 20.
Artigo
Inglês
| MEDLINE | ID: mdl-29392164
12.
Detection of Membrane Protein Interactions by Cell-based Tango Assays.
Bio Protoc
; 7(22)2017 Nov 20.
Artigo
Inglês
| MEDLINE | ID: mdl-29392165
13.
Streptavidin Bead Pulldown Assay to Determine Protein Homooligomerization.
Bio Protoc
; 7(22)2017 Nov 20.
Artigo
Inglês
| MEDLINE | ID: mdl-29392166
14.
A D53 repression motif induces oligomerization of TOPLESS corepressors and promotes assembly of a corepressor-nucleosome complex.
Sci Adv
; 3(6): e1601217, 2017 06.
Artigo
Inglês
| MEDLINE | ID: mdl-28630893
15.
Alzheimer's disease-associated mutations increase amyloid precursor protein resistance to γ-secretase cleavage and the Aß42/Aß40 ratio.
Cell Discov
; 2: 16026, 2016.
Artigo
Inglês
| MEDLINE | ID: mdl-27625790
16.
Crystal structures of two phytohormone signal-transducing α/ß hydrolases: karrikin-signaling KAI2 and strigolactone-signaling DWARF14.
Cell Res
; 23(3): 436-9, 2013 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-23381136